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FLCN
英文名:Rabbit Monoclonal Antibody
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| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308113595-100ul | 現貨 | 0 | ¥0 |
| 別 名 | FLCN antibody, BHD antibody, DKFZp547A118 antibody, FLCL antibody, FLJ45004 antibody, FLJ99377 antibody, MGC17998 antibody, MGC23445 antibody, Folliculin antibody, BHD skin lesion fibrofolliculoma protein antibody, Birt-Hogg-Dube syndrome protein antibody |
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| 產品參數 | 【產品介紹】Folliculin, or FLCN, functions as a
tumor suppressor. It forms a complex with novel folliculin-interacting proteins 1 and 2 (FNIP1 and FNIP2), and 5'-AMP-activated protein kinase (AMPK), an important energy sensor in cells that negatively regulates mammalian target of rapamycin (mTOR) (1). FLCN is associated with Smith-Magenis syndrome. Mutations in FLCN are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax (2). Recommended Applications WB Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 Species Reactivity * Human, Mouse, Rat *Species cross-reactivity is based on WB analysis Products Data Western blot analysis on (A) 293T and (B) NCCIT cell lysates using anti-FLCN RabMAb (cat. #3929-1). Specificity A recombinant GST-tagged protein fragment corresponding to human FLCN was used as an immunogen. This antibody was developed as part of a collaboration between Epitomics, the National Cancer Institute's Center for Cancer Research and the lab of Marston Linehan. |
| 性狀 | 【反應特異性】Human , Mouse , Rat
【克隆 ID】EPNCIR147 【用途】WB 【抗原分子量】70kDa |
| 貯存 | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |
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