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FKBP4
英文名：Rabbit Monoclonal Antibody
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檢測信息查詢
| 貨號 | 規(guī)格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308113592-100ul | 現(xiàn)貨 | 0 | ￥0 |
| 別 名 | FKBP4 antibody, FKBP51 antibody, FKBP52 antibody, FKBP59 antibody, HBI antibody, Hsp56 antibody, PPIase antibody, p52 antibody, Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed antibody, Immunophilin FKBP52 antibody, Rotamase antibody |
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| 產(chǎn)品參數(shù) | 【產(chǎn)品介紹】FKBP4 is a member of the immunophilin
protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. FKBP4 interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes. It is known to associate with phytanoyl-CoA alpha-hydroxylase, and it can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. FKBP4 correlates strongly with adeno-associated virus type 2 vectors (AAV) resulting in a significant increase in AAV-mediated transgene expression in human cell lines. Thus this protein is thought to have important implications for the optimal use of AAV vectors in human gene therapy (1). Recommended Applications WB, IHC, IP, FC Applications and Recommended Dilution Factors WB: 1:50,000 - 200,000 IHC: 1:100 - 250 IP: 1:10 - 100 FC: 1:10 - 100 Species Reactivity * Human *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) HeLa, (B) MCF-7, (C) Jurkat, and (D) K562 cell lysates using anti-FKBP4 RabMAb (cat. #5241-1). Immunohistochemical analysis of paraffin-embedded human breast tissue using anti-FKBP4 RabMAb (cat. #5241-1). Specificity A synthetic peptide corresponding to residues near the C-terminus of human FKBP4 was used as an immunogen. |
| 性狀 | 【反應(yīng)特異性】Human
【克隆 ID】EPR6619 【用途】WB , IHC , FC , IP 【抗原分子量】52kDa |
| 貯存 | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |
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