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FKBP6
英文名：Rabbit Monoclonal Antibody
Cas號：
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檢測信息查詢
| 貨號 | 規(guī)格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308113593-100ul | 現(xiàn)貨 | 0 | ￥0 |
| 別 名 | FKBP6 antibody, FKBP36 antibody, MGC87179 antibody, PPIase antibody, Peptidyl-prolyl cis-trans isomerase FKBP6 antibody, Immunophilin FKBP36 antibody, Rotamase antibody |
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| 產(chǎn)品參數(shù) | 【產(chǎn)品介紹】FK506 binding protein 6 (FKBP6) is a
cellular receptor for the immunosuppressants FK506 and rapamycin in the immunophilin FKBP family (1). FKBP's are involved in several biochemical processes including protein folding, receptor signaling, protein trafficking and transcription (2). It forms a complex as FKBP-FK506 to competitively bind to and inhibit the Calcium- and calmodulin-dependent phosphatase calcineurin (3). FKBP6 plays a role in sex-specific fertility as a component of the synaptonemal complex, which is essential for chromosome pairing and meiotic division (4). A genetic deletion in FKBP6 is associated with Williams-Beuren syndrome (WBS), a neurodevelopmental disorder (5). Recommended Applications WB, IHC, FC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 IHC: 1 : 100 -250 FC: 1 : 10 -100 Species Reactivity Human, Mouse, Rat Products Data Western blot analysis on (A) Molt-4 and (B) SAOS-2 cell lysates using anti-FKBP6 RabMAb (cat. # 2850-1). Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-FKBP6 RabMAb (cat. #2850-1). Specificity A synthetic peptide corresponding to residues near the C-terminus in human FKBP6 was used as an immunogen. |
| 性狀 | 【反應(yīng)特異性】Human , Mouse , Rat
【克隆 ID】EPR3674 【用途】WB , IHC , FC 【抗原分子量】38kDa |
| 貯存 | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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