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Crk/p38 (CRK)
英文名：Rabbit Monoclonal Antibody
Cas號(hào)：
Cas號(hào)：
檢測(cè)信息查詢
| 貨號(hào) | 規(guī)格 | 貨期 | 庫存 | 價(jià)格 | 促銷價(jià) | 訂購(gòu) |
| 1308113466-100ul | 現(xiàn)貨 | 0 | ￥0 |
| 別 名 | CRK antibody, CRKII antibody, Adapter molecule crk antibody, Proto-oncogene c-Crk antibody, p38 antibody |
| Cas號(hào) | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 產(chǎn)品參數(shù) | 【產(chǎn)品介紹】Crk (p38) are adaptor proteins, composed
mostly of SH2 and SH3 domains, which play a key role in cellular signaling by mediating the construction of protein complexes and also by managing cell proliferation, differentiation, and migration (1). They are critical integrators of upstream signals for cell invasion and migration in human cancer cell lines. Crk is believed to be a regulator of invasive responses because increased levels of the protein have been observed in multiple human cancers (2). In vivo studies have demonstrated that decreased levels of Crk remarkably inhibits tumor formation and its invasive growth (3). Crk associates with ERM family proteins (including ezrin, radixin, and moesin), activates RhoA, and promotes cell motility toward hyaluronic acid (4). Recommended Applications WB, ICC, IP, FC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 ICC: 1:50 - 100 IP: 1:10 - 100 FC: 1:100 - 500 Species Reactivity * Human, Mouse, Rat *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) HepG2, (B) K562, (C) HeLa, and (D) Jurkat cell lysates using anti-Crk/p38 RabMAb (cat. #5359-1). Flow cytometric analysis of permeabilized HepG2 cells using anti-Crk/p38 RabMAb (red) (catalog # 5359-1) or a rabbit IgG (negative) (green). Specificity A synthetic peptide corresponding to residues in human Crk/p38 was used as an immunogen. |
| 性狀 | 【反應(yīng)特異性】Human , Mouse , Rat
【克隆 ID】EPR4984(2) 【用途】WB , ICC , FC , IP 【抗原分子量】38kDa |
| 貯存 | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |
滬公網(wǎng)安備 31012002003054號(hào)