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Recombinant Human Activation-inducible TNF-related Ligand/AITRL
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檢測信息查詢
| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308132829-10 μg | 0 | ￥3800 | ||||
| 1308132829-50 μg | 0 | ￥9800 |
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| 性狀 | Recombinant Human Activation-inducible TNF-related Ligand/AITRL 是在 E. coli 中產生的單一非糖基化的多肽鏈，分子量為 14.3kDa。
Synonyms rHuActivation-inducible TNF-related Ligand/AITRL; TNFSF18; GITRL; TL-6; rHuAITRL Species Human Source E. coli Accession Q9UNG2 Gene ID 8995 Molecular Weight Approximately 14.3 kDa AA Sequence METAKEPCMA KFGPLPSKWQ MASSEPPCVN KVSDWKLEIL QNGLYLIYGQ VAPNANYNDV APFEVRLYKN KDMIQTLTNK SKIQNVGGTY ELHVGDTIDL IFNSEHQVLK NNTYWGIILL ANPQFI Biological Activity The ED50 is <5 ng/mL as measured by PMBC, corresponding to a specific activity of >2 × 105 units/mg. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against 50 mM Tris, pH 8.0. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human Activation-inducible TNF-related Ligand/AITRL (rHuActivation-inducible TNF-related Ligand/AITRL) to 100 μg/mL using ddH2O. Storage & Stability Lyophilized recombinant Human Activation-inducible TNF-related Ligand/AITRL (rHuActivation-inducible TNF-related Ligand/AITRL) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Human activation-inducible tumor necrosis factor receptor (AITR) and its ligand, AITRL, are important costimulatory molecules in the pathogenesis of autoimmune diseases. AITR and AITRL are both costimulatory molecules, which are pairs of molecules that interact with each other and are expressed at high levels on the surface of CD4+ CD25+ T cells. When these costimulatory molecules are activated, they inhibit the ability of the CD4+ CD25+ T cells to suppress the autoreactive T-cells. This results in an increased autoimmune response[1]. |
| 貯存 |
- Recombinant Human WISP-1 (CHO-expressed)
- Recombinant Human Epidermal Growth Factor Receptor, His (Sf9 insect cells-expressed)
- Recombinant Human 4-1BB, Fc Chimera (CHO-expressed)
- Recombinant Human Activation-inducible TNF-related Ligand/AITRL
- Recombinant Mouse Activation-inducible TNF-related Ligand/AITRL
- Recombinant Mouse April/TNFSF13
- Recombinant Human B7-1/CD80, Fc Chimera (HEK293-expressed)
- Recombinant Human B7-2/CD86, Fc Chimera (HEK293-expressed)
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