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Recombinant Human 4-1BB, Fc Chimera (CHO-expressed)
英文名：
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檢測信息查詢
| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308132827-10 μg | 0 | ￥1800 | ||||
| 1308132827-50 μg | 0 | ￥3800 |
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| 性狀 | Recombinant Human 4-1BB, Fc Chimera (CHO-expressed) 是在 CHO 中產生的 C-末端標記 IgG1 Fc 片段的多肽鏈。4-1BB 是腫瘤壞死因子受體超家族的成員。
Synonyms rHu4-1BB, Fc Chimera; CD137; ILA Species Human Source CHO Accession Q07011 Gene ID 3604 Molecular Weight 55-60 kDa AA Sequence LQDPCSNCPA GTFCDNNRNQ ICSPCPPNSF SSAGGQRTCD ICRQCKGVFR TRKECSSTSN AECDCTPGFH CLGAGCSMCE QDCKQGQELT KKGCKDCCFG TFNDQKRGIC RPWTNCSLDG KSVLVNGTKE RDVVCGPSPA DLSPGASSVT PPAPAREPGH SPQ Biological Activity Binding ability is measured by immobilized ELISA, 1 μg/mL (100 μL/well) of immoblized recombinant human 4-1BB-Fc Chimera produces 50% optimal binding response approximately 5-15 ng/mL. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human 4-1BB, Fc Chimera (CHO-expressed) (rHu4-1BB, Fc Chimera) to 100 μg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Human 4-1BB, Fc Chimera (CHO-expressed) (rHu4-1BB, Fc Chimera) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background 4-1BB:4-1BBL are a member of the TNFR:TNF ligand family, which are expressed on T cells and antigen-presenting cells (APCs), respectively. Therapies utilizing the 4-1BB:4-1BBL signaling pathway have been shown to have antitumor effects in a number of model systems. 4-1BB:4-1BBL costimulation has be used for the immunotherapy of cancer[1]. |
| 貯存 |
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