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那他珠單抗
英文名：natalizuMab
Cas號：189261-10-7
Cas號：189261-10-7
檢測信息查詢
| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308132499-1mg | 0 | ￥0 | ||||
| 1308132499-5mg | 0 | ￥0 |
| 別 名 | Immunoglobulin G4,anti-(human integrin R4) (human-mouse monoclonal AN100226 c4-chain),disulfide with human-mouse monoclonal AN100226 light chain,dimer |
| Cas號 | 189261-10-7 |
| M D L | |
| 分子式 | C40H55N7O11S |
| 分子量 | 841.97 |
| 產品參數 | Description
Natalizumab is a recombinant, humanized monoclonal antibody, binds to α4β1-integrin and blocks its interaction with vascular cell adhesion molecule-1 (VCAM-1). Natalizumab can be used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease. Natalizumab is also the first targeted therapy which blocks an essential mechanism for lymphocyte entry to the CNS and thus prevents acute demyelinating relapses[1]. |
| 性狀 | Natalizumab 是一種重組的人源化單克隆抗體，與 α4β1-整聯蛋白 (α4β1-integrin) 結合并阻斷其與血管細胞粘附分子 1 (VCAM-1) 的相互作用。Natalizumab 可用于治療復發緩解型多發性硬化癥和克羅恩氏病。Natalizumab 也可阻止淋巴細胞進入中樞神經系統，從而防止急性脫髓鞘復發 |
| 貯存 | SMILES [Natalizumab] Storage Please store the product under the recommended conditions in the Certificate of Analysis. References [1]. Hutchinson M. Natalizumab: A new treatment for relapsing remitting multiple sclerosis. Ther Clin Risk Manag. 2007 Jun;3(2):259-68. |
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