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Abatacept
英文名:Unii-7D0yb67S97
Cas號:332348-12-6
Cas號:332348-12-6
檢測信息查詢
| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 13081324961-1mg | 99.00% | 0 | ¥11000 | |||
| 13081324961-5mg | 99.00% | 0 | ¥19600 |
| 別 名 | Unii-7D0yb67S97 |
| Cas號 | 332348-12-6 |
| M D L | |
| 分子式 | |
| 分子量 | |
| 產品參數 | Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Description Abatacept (CTLA4lg) is a soluble fusion protein consisting of the extra-cellular domain of human CTLA4 and a fragment of the Fc portion of human IgG1 (hinge and CH2 and 3 domains)[1]. Abatacept is a selective T-cell co-stimulation modulator and a protein drug for the autoimmune diseases[2]. |
| 性狀 | Abatacept (CTLA4lg) 是一種可溶性融合蛋白,由人 CTLA4 的胞外結構域和人 IgG1 Fc 部分的片段 (鉸鏈,CH2 和 3 結構域) 組成。Abatacept 是選擇性 T 細胞共刺激調節劑,也是一種用于自身免疫性疾病的蛋白藥物。 |
| 貯存 | Storage Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month References [1]. Kiykim A, et al. Abatacept as a Long-Term Targeted Therapy for LRBA Deficiency. J Allergy Clin Immunol Pract. 2019 Jun 22. [2]. Lon HK, et al. Modeling pharmacokinetics/pharmacodynamics of abatacept and disease progression in collagen-induced arthritic rats: a population approach. J Pharmacokinet Pharmacodyn. 2013 Dec;40(6):701-12. [3]. Patakas A, et al. Abatacept Inhibition of T Cell Priming in Mice by Induction of a Unique Transcriptional Profile That Reduces Their Ability to Activate Antigen-Presenting Cells. Arthritis Rheumatol. 2016 Mar;68(3):627-38. |
- 維多珠單抗 943609-66-3
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- Human IgG1 Control
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- BENRALIZUMAB 1044511-01-4
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