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LDL Receptor (C-term) (LDLR)
英文名：LDL Receptor (C-term) (LDLR)
Cas號：
Cas號：
檢測信息查詢
| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308114489-100ul | 現貨 | 0 | ￥0 |
| 別 名 | LDLR antibody, FH antibody, FHC antibody, LDLCQ2 antibody, Low-density lipoprotein receptor antibody, antibody |
| Cas號 | |
| M D L | |
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| 分子量 | |
| 產品參數 | 【產品介紹】The low density lipoprotein (LDL)
receptor system coordinates the metabolism of cholesterol, an essential component of the plasma membrane of all mammalian cells. Study of this system has led to an enhanced understanding of the cellular basis of cholesterol homeostasis. It has also brought into focus an important mechanism of metabolic regulation--the process of receptor- mediated endocytosis (1). Data suggest that the juxtamembranous region of the cytoplasmic domain participates in protein:protein interactions that allow the low density lipoprotein receptor to cluster in coated pits (2). It has been shown that the family of LDL receptors may serve as viral receptors. Endocytosis of the Flaviviridae viruses, hepatitis C virus, GB virus C/hepatitis G virus, and bovine viral diarrheal virus (BVDV) was shown to be mediated by LDL receptors on cultured cells (3). Recommended Applications WB, IHC, ICC, IP, FC Applications and Recommended Dilution Factors WB: 1:1000 - 10,000 IHC: 1:100 - 250 ICC: 1:100 - 250 IP: 1:50 FC: 1:70 Species Reactivity * Human, Mouse, Rat *For Mouse, this antibody is recommended for WB only Rat cross reactivity tested by western blot only Products Data A. Western blot analysis on HepG2 cell lysate using anti-LDL receptor RabMAb (cat. # 1956-1), dilution 1:5000. B. Immunohistochemical staining of paraffin-embedded human liver using anti-LDLR RabMAb (cat. #1956-1). C. Immunofluorescent staining of HEPG2 cells using anti-LDLR RabMAb (cat. #1956-1). Specificity A synthetic peptide corresponding to residues on the C-terminus of human LDL receptor was used as an immunogen. This antibody detects both isoforms of LDL receptor. |
| 性狀 | 【產品類型】Rabbit Monoclonal Antibody
【反應特異性】Human , Mouse , Rat 【克隆 ID】EP1553Y 【用途】WB , IHC , ICC , FC , IP 【產品性狀】 【陽性對照】 【產品濃度】 【細胞定位】 【抗原分子量】140/160 (2 isoforms) |
| 貯存 | Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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