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HLA-DRB1
英文名：HLA-Drb1
Cas號：
Cas號：
檢測信息查詢
| 貨號 | 規(guī)格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308114405-100ul | 現(xiàn)貨 | 0 | ￥0 |
| 別 名 | HLA-DRB1 antibody, DRB1 antibody, DRw10 antibody, FLJ75017 antibody, FLJ76359 antibody, HLA-DR1B antibody, HLA-DRB antibody, HLA-DRB1* antibody, SS1 antibody, HLA class II histocompatibility antigen, DRB1-1 beta chain antibody, MHC class II antigen DRB1*1 |
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| 產(chǎn)品參數(shù) | 【產(chǎn)品介紹】HLA-Drb1 belongs to the HLA class II beta
chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of HLA-Drb1 variations have been described, and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. HLA-Drb1 is expressed at a level five times higher than its paralogs DRB3, DRB4 and DRB5. HLA-Drb1 is present in all individuals. Variants of HLA-Drb1 are linked with either none or one of the proteins for DRB3, DRB4 and DRB5 (1). Recommended Applications WB, IHC, ICC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 IHC: 1:100 - 250 ICC: 1:100 - 250 Species Reactivity * Human *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) human spleen, (B) lymph node, (C) Ramos, and (D) human tonsil lysates using anti-HLA-Drb1 RabMAb (cat. #5352-1). Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-HLA-Drb1 RabMAb (cat. #5352-1). Specificity A synthetic peptide corresponding to residues in human HLA-Drb1 was used as an immunogen. |
| 性狀 | 【產(chǎn)品類型】Rabbit Monoclonal Antibody
【反應(yīng)特異性】Human 【克隆 ID】EPR6148 【用途】WB , IHC , ICC 【產(chǎn)品性狀】 【陽性對照】 【產(chǎn)品濃度】 【細(xì)胞定位】 【抗原分子量】30kDa |
| 貯存 | Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |
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