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HLA-B
英文名：HLA-B
Cas號：
Cas號：
檢測信息查詢
| 貨號 | 規(guī)格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308114402-100ul | 現貨 | 0 | ￥0 |
| 別 名 | HLA-B antibody, AS antibody, Bw-45 antibody, Bw-48 antibody, Bw-56 antibody, HLA-B-5601 antibody, HLA-B-6701 antibody, HLA-B27 antibody, HLA-B73 antibody, HLAB antibody, MGC111087 antibody, SPDA1 antibody, HLA class I histocompatibility antigen, B-7 alpha |
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| 產品參數 | 【產品介紹】HLA-B belongs to the HLA class I heavy
chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide; exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide; exon 4 encodes the alpha3 domain; exon 5 encodes the transmembrane region; and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class I molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described. Recommended Applications WB, IHC, ICC, IP Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 IHC: 1:100 - 250 ICC: 1:250 - 500 IP: 1:10 - 100 Species Reactivity Human Products Data Western blot analysis on (A) Ramos, (B) HL-60, (C) Jurkat, and (D) TF-1 cell lysates using anti-HLA-B RabMAb (cat. # 2389-1). Immunohistochemical staining of paraffin-embedded human tonsils using anti-HLA-B RabMAb (cat. #2389-1). Specificity A synthetic peptide corresponding to residues in human HLA-B was used as an immunogen. |
| 性狀 | 【產品類型】Rabbit Monoclonal Antibody
【反應特異性】Human 【克隆 ID】EP2624 【用途】WB , IHC , ICC , IP 【產品性狀】 【陽性對照】 【產品濃度】 【細胞定位】 【抗原分子量】44kDa |
| 貯存 | Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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