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CD3 epsilon (CD3E)
英文名：Rabbit Monoclonal Antibody
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檢測信息查詢
| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308113420-100ul | 現貨 | 0 | ￥3000 |
| 別 名 | CD3E antibody, FLJ18683 antibody, T3E antibody, TCRE antibody, T-cell surface glycoprotein CD3 epsilon chain antibody, T-cell surface antigen T3/Leu-4 epsilon chain antibody |
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| 產品參數 | 【產品介紹】CD3 (Cluster of Differentiation 3) is a
complex of proteins that associates directly with the T cell antigen receptor (TCR) (1). Antigen binding to the TCR leads to IL-2 secretion via activation of a tyrosine phosphorylation pathway and a phospholipase C (PLC) pathway, in turn activating protein kinase C (1,2). CD3 is composed of five invariant polypeptide chains that associate to form three dimers. The five invariant chains of CD3 are labeled gamma, delta, epsilon, zeta, and eta. The gamma, epsilon and delta chains each contain a single copy of a conserved immunoreceptor tyrosine-based activation motif (ITAM). Phosphorylated ITAMs act as docking sites for protein kinases such as ZAP-70 and Syk (3). Recommended Applications WB, IHC, IP Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 IHC: 1:250 - 500 IP: 1:50 Species Reactivity * Human *Cross reactivity determined by western blot only. Products Data A. Western blot analysis on Jurkat cell lysate of using anti-CD3 epsilon Rabbit Monoclonal (cat. # 1774-1). B. Immunohistochemical analysis of paraffin-embedded human spleen using anti-CD3 epsilon Rabbit Monoclonal (cat. #1774-1). Specificity A synthetic peptide corresponding to residues in cytoplasmic domain of human CD3 epsilon was used as immunogen. The antibody does not cross-react with other subunits of CD3. |
| 性狀 | 【反應特異性】Human
【克隆 ID】EP449E 【用途】WB , IHC , IP 【抗原分子量】23kDa |
| 貯存 | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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