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Caspase-2
英文名：Rabbit Monoclonal IgG
Cas號：
Cas號：
檢測信息查詢
| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308113400-100ul | 現貨 | 0 | ￥0 |
| 別 名 | CASP-2, ICH-1 protease, NEDD2 protein, Neural precurs o r cell expressed developmentally down-regulated protein 2, NEDD-2 |
| Cas號 | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 產品參數 | 【產品介紹】Caspase-2 (Nedd2/ICH-1) is part of a family
of aspartate-specific cysteine proteases that participate in programmed cell death, o r apoptosis. Caspase-2 is localized to the nucleus, a n d has been shown to play roles in both positive a n d negative regulation of apoptosis (1). Upon apoptotic stimulation, pro-caspase-9 is cleaved in a series of steps to produce an 18-kDa large subunit a n d a 12-kDa small fragment (2). Caspase-2 can be a nuclear initiat o r caspase, as it has been shown to precede the processing a n d activation of caspase-8, -9, a n d -3 (3). Caspase-2 might also act as an effect o r caspase; in apoptotic pathways resulting from UV-induced DNA damage, processing of caspase-2 occurs downstream of caspase-9 a n d caspase-3 activation (4). WB: 1:500 IP: 1:20 A. Western blot analysis on Jurkat cell lysate using anti-Caspase-2 RabMAb (catalog #1552-1), dilution 1:500. |
| 性狀 | 【反應特異性】Human
【克隆 ID】Y154 【用途】WB , IP 【抗原分子量】48/18 kDa |
| 貯存 |
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