小程序掃碼下單
本網站銷售的所有產品僅用于工業應用或者科學研究等非醫療目的，不可用于人類或動物的臨床診斷或者治療，非藥用，非食用。
Caldesmon Phospho (pT753) (CALD1)
英文名：Rabbit Monoclonal Antibody
Cas號：
Cas號：
檢測信息查詢
| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308113387-100ul | 現貨 | 0 | ￥0 |
| 別 名 | CALD1 antibody, CDM antibody, H-CAD antibody, HCAD antibody, L-CAD antibody, LCAD antibody, MGC21352 antibody, NAG22 antibody, Caldesmon antibody, antibody |
| Cas號 | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 產品參數 | 【產品介紹】Caldesmon is a smooth muscle and
nonmuscle regulatory protein that interacts with actin, myosin, tropomyosin, and calmodulin (1,2). Smooth muscle caldesmon is an elongated molecule with a calmodulin, tropomyosin, and actin-binding region at the C-terminus and a myosin-binding domain at the N-terminus (3). Caldesmon stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, caldesmon inhibits the actomyosin ATPase by binding to F-actin. This inhibition is reduced by calcium-calmodulin and is promoted by tropomyosin (4). Phosphorylation of non-muscle caldesmon has been linked to reduction of caldesmon's binding properties to actin, myosin, and calmodulin. Also, caldesmon's inhibition of actomyosin ATPase is reduced with its Phosphorylation (5). Recommended Applications WB, ICC Applications and Recommended Dilution Factors WB: 1:1000 - 5000 ICC: 1:50 - 100 Species Reactivity Human Products Data Western blot analysis on HeLa cell lysates using anti-Phospho-Caldesmon (pT753) RabMAb (cat. # 2394-1), 1:5000 dilution. Cells were either (A) untreated (B) treated with Calyculin A. |
| 性狀 | 【反應特異性】Human
【克隆 ID】EPR2211Y 【用途】WB , ICC 【抗原分子量】120-150 (smooth muscle)/70-80 |
| 貯存 |
滬公網安備 31012002003054號