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Recombinant Human Twisted Gastrulation, His
英文名：
Cas號(hào)：
Cas號(hào)：
檢測(cè)信息查詢
| 貨號(hào) | 規(guī)格 | 貨期 | 庫(kù)存 | 價(jià)格 | 促銷價(jià) | 訂購(gòu) |
| 1308132935-10 μg | 0 | ￥2200 | ||||
| 1308132935-50 μg | 0 | ￥4200 |
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| 性狀 | Recombinant Human Twisted Gastrulation, His 是帶有標(biāo)簽的人重組 Twisted gastrulation。Recombinant Human Twisted Gastrulation 對(duì)預(yù)激活 T 細(xì)胞 (包括 IL-2、IL-4、IFN-γ 和 IL-10) 的 CD3 介導(dǎo)的增殖和細(xì)胞因子產(chǎn)生具有有效的抑制作用
Synonyms rHuTwisted Gastrulation, His; TWSG1 ; 重組人扭曲原腸形成，His 標(biāo)簽 Species Human Source HEK 293 Accession Q9GZX9 Gene ID 57045 Molecular Weight 30-33 kDa AA Sequence HHHHHHHHCN KALCASDVSK CLIQELCQCR PGEGNCSCCK ECMLCLGALW DECCDCVGMC NPRNYSDTPP TSKSTVEELH EPIPSLFRAL TEGDTQLNWN IVSFPVAEEL SHHENLVSFL ETVNQPHHQN VSVPSNNVHA PYSSDKEHMC TVVYFDDCMS IHQCKISCES MGASKYRWFH NACCECIGPE CIDYGSKTVK CMNCMF Biological Activity The ED50 is <2 μg/mL as measured by ATDC-5 chondrogenic cells. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human Twisted Gastrulation, His (rHuTwisted Gastrulation, His) to 100 μg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Human Twisted Gastrulation, His (rHuTwisted Gastrulation, His) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Twisted gastrulation (TSG) is one of the genes regulated by Tob and acts as an inhibitor of activated mature CD4+ human T lymphocytes. Recombinant Tsg had a potent inhibitory effect on CD3-mediated proliferation and cytokine production of preactivated T cells, including IL-2, IL-4, IFN-γ, and IL-10. Tsg is a potent agonist of TGF-β downstream signaling in activated human CD4+ T cells and suggest that enhancement of TGF-β mediating signaling by Tsg may represent a novel target for molecular intervention for control of aberrant T-cell responses during ongoing graft-versus-host disease (GVHD) and autoimmune diseases[1]. |
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