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Recombinant Human PD-1, Fc Chimera (CHO-expressed)
英文名:
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| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308132911-50 μg | 0 | ¥4400 | ||||
| 1308132911-100 μg | 0 | ¥7800 |
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| 性狀 | Recombinant Human PD-1, Fc Chimera (CHO-expressed) 當與T細胞受體的配體PD-L1或PD-L2結合時,抑制T細胞受體的激活信號。
Synonyms rHuPD-1, Fc Chimera; PD1; CD279; PDCD1 ; 重組人PD-1, Fc Chimera (CHO 表達) Species Human Source CHO Accession Q15116 Gene ID 5133 Molecular Weight 60-65 kDa AA Sequence LDSPDRPWNP PTFSPALLVV TEGDNATFTC SFSNTSESFV LNWYRMSPSN QTDKLAAFPE DRSQPGQDCR FRVTQLPNGR DFHMSVVRAR RNDSGTYLCG AISLAPKAQI KESLRAELRV TERRAEVPTA HPSPSPRPAG QFQ Biological Activity 1 μg/mL (100 μL/well) of immoblized recombinant human PD-L1/B7-H1-Fc can bind human Biotin-PD-1-Fc with a linear range of 0.1-1 μg/mL. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human PD-1, Fc Chimera (CHO-expressed) (rHuPD-1, Fc Chimera) to 100 μg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Human PD-1, Fc Chimera (CHO-expressed) (rHuPD-1, Fc Chimera) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Programmed death-1 (PD-1) is a receptor on T cells that has been shown to suppress activating signals from the T cell receptor when bound by either of its ligands, programmed death-ligand 1 (PD-L1) or PD-L2. When PD-1 expressing T cells contact cells expressing its ligands, functional activities in response to antigenic stimuli, including proliferation, cytokine secretion, and cytotoxicity are reduced[1]. |
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- Recombinant Human PD-1, Fc Chimera (CHO-expressed)
- Recombinant Human PD-1, His (HEK293-expressed)
- Recombinant Human PD-L1, Fc Chimera (CHO-expressed)
- Recombinant Human PD-L1, His (HEK293-expressed)
- Recombinant Human PD-L2, Fc Chimera (HEK293-expressed)
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