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Recombinant Human OX40/TNFRSF4, His (HEK293-expressed)
英文名:
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| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308132910-10 μg | 0 | ¥3200 | ||||
| 1308132910-50 μg | 0 | ¥7800 |
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| 性狀 | Recombinant Human OX40/TNFRSF4, His (HEK293-expressed) 通過與受體蛋白TRAF2和TRAF5的相互作用激活NF-kappaB。Recombinant Human OX40/TNFRSF4, His (HEK293-expressed) 促進凋亡抑制因子BCL2和BCL2lL1/BCL2-XL的表達,從而抑制細胞凋亡。
Synonyms rHuOX40/TNFRSF4, His; ACT35 antigen; CD134; TXGP1L ; 重組人Human OX40/TNFRSF4, His (HEK293-表達) Species Human Source HEK 293 Accession P43489 Gene ID 7293 Molecular Weight 40-45 kDa AA Sequence LHCVGDTYPS NDRCCHECRP GNGMVSRCSR SQNTVCRPCG PGFYNDVVSS KPCKPCTWCN LRSGSERKQL CTATQDTVCR CRAGTQPLDS YKPGVDCAPC PPGHFSPGDN QACKPWTNCT LAGKHTLQPA SNSSDAICED RDPPATQPQE TQGPPARPIT VQPTEAWPRT SQGPSTRPVE VPGGRAVAHH HHHH Biological Activity 2 μg/mL (100 μL/well) of immoblized recombinant human OX40/TNFRSF4-His can bind human Biotin-OX40L-His with a linear range of 1.22-19.53 ng/mL. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS, 5% trehalose and mannitol. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human OX40/TNFRSF4, His (HEK293-expressed) (rHuOX40/TNFRSF4, His) to 100 μg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Human OX40/TNFRSF4, His (HEK293-expressed) (rHuOX40/TNFRSF4, His) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background OX40/TNFRSF4 has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that OX40/TNFRSF4 promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis[1]. |
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