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JNK2 (MAPK9)
英文名：JNK2 (MAPK9)
Cas號：
Cas號：
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| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308114472-100ul | 現貨 | 0 | ￥0 |
| 別 名 | MAPK9 antibody, JNK-55 antibody, JNK2 antibody, JNK2A antibody, JNK2ALPHA antibody, JNK2B antibody, JNK2BETA antibody, PRKM9 antibody, SAPK antibody, p54a antibody, p54aSAPK antibody, Mitogen-activated protein kinase 9 antibody, JNK-55 antibody, Stress-ac |
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| 產品參數 | 【產品介紹】JNK protein kinases are distantly related
to mitogen-activated protein kinases (ERKs) and are activated by dual phosphorylation on Tyr and Thr. The JNK protein kinase group includes the 46-kDa isoform JNK1 and the 55-kDa protein kinase JNK2. The activities of both JNK isoforms are markedly increased by exposure of cells to UV radiation (1). JNK becomes activated in vivo in response to pro-inflammatory cytokines or cellular stresses. Its full activation requires the phosphorylation of a threonine and a tyrosine residue in a Thr-Pro-Tyr motif, which can be catalysed by the protein kinases mitogen-activated protein kinase kinase MKK4 and MKK7 (2). JNK2 functions in a cell-type-specific and stimulus-dependent manner, being required for apoptosis of immature thymocytes induced by anti-CD3 antibody but not for apoptosis induced by anti-Fas antibody, UVC or dexamethasone. JNK2 is not required for activation-induced cell death of mature T cells (3). Recommended Applications WB, IHC, ICC, IP, FC Applications and Recommended Dilution Factors WB: 1:2,000 - 50,000 IHC: 1:100 - 250 ICC: 1:100 - 250 IP: 1:100 FC: 1:40 Species Reactivity * Human, Mouse, Rat *For Mouse, this antibody is recommended for WB only Rat cross reactivity tested by western blot only Products Data A. Western blot analysis on HeLa cell lysate using anti-JNK2 RabMAb (cat. # 2037-1), dilution 1:50,000. B. Immunohistochemical staining of paraffin-embedded human breast carcinoma using anti-JNK2 RabMAb (cat. #2037-1). Specificity A synthetic peptide corresponding to residues near the C-terminus of human JNK2 was used as an immunogen. |
| 性狀 | 【產品類型】Rabbit Monoclonal Antibody
【反應特異性】Human , Mouse , Rat 【克隆 ID】EP1595Y 【用途】WB , IHC , ICC , FC , IP 【產品性狀】 【陽性對照】 【產品濃度】 【細胞定位】 【抗原分子量】54/46kDa |
| 貯存 | Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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