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IRS-1 Phospho (pY896)
英文名：IRS-1 Phospho (pY896)
Cas號：
Cas號：
檢測信息查詢
| 貨號 | 規(guī)格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308114461-100ul | 現(xiàn)貨 | 0 | ￥0 |
| 別 名 | IRS-1 |
| Cas號 | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 產(chǎn)品參數(shù) | 【產(chǎn)品介紹】Insulin recept o r substrates (IRS), the
maj o r intracellular substrates of the insulin recept o r (IR), are adapt o r proteins that transduce signals from the IR to downstream effect o r s that are imp o r tant f o r the biological effect of insulin (1-2). After insulin stimulation, IRS proteins are rapidly phosph o r ylated on multiple tyrosine residues. Once phosph o r ylated, IRS proteins bind a n d activate Grb-2, SHP2 a n d the PI3-K p85 subunit (2-3). IRS-1 functions as one of the key regulat o r s of IR a n d the insulin-like growth fact o r -1 recept o r . Disruption of IRS-1 causes growth retardation a n d insulin resistance associated with hypertension, hypertriglyceridemia, a n d impaired endothelium-dependent vascular relaxation (4-5) WB: 1:500,000 A. Western blot analysis on 293 cell lysates using anti-Phospho-IRS-1 (pY896) RabMAb (cat. #1813-1), 1:500,000 dilution. Cells were either (A) untreated (B) treated with insulin |
| 性狀 | 【產(chǎn)品類型】Rabbit Monoclonal IgG
【反應(yīng)特異性】Human , Mouse , Rat 【克隆 ID】EP260Y 【用途】WB 【產(chǎn)品性狀】 【陽性對照】 【產(chǎn)品濃度】 【細(xì)胞定位】 【抗原分子量】170 kDa |
| 貯存 |
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