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Alpha-Actinin 2
英文名：Alpha-Actinin 2
Cas號：
Cas號：
檢測信息查詢
| 貨號 | 規(guī)格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308114369-100ul | 現(xiàn)貨 | 0 | ￥3575 |
| 別 名 | ACTN2, Alpha-actinin-2, Alpha-actinin skeletal muscle isoform 2;F-actin cross-linking protein |
| Cas號 | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 產(chǎn)品參數(shù) | 【產(chǎn)品介紹】Alpha-actinin is a ubiquitously
expressed protein found in numerous actin structures. It consists of an N-terminal actin binding domain, a central rod domain, a n d a C-terminal domain a n d functions as a homodimer to cross-link actin filaments. The rod domain determines the distance between cross-linked actin filaments a n d also serves as an interaction site f o r several cytoskeletal a n d signaling proteins (1). Alpha-actinins are a multigene family of four actin-binding proteins related to dystrophin. The two skeletal muscle isof o r ms of alpha-actinin (ACTN2 a n d ACTN3) are maj o r structural components of the Z-line involved in anch o r ing the actin-containing thin filaments. In humans, ACTN2 is expressed in all muscle fibers, while ACTN3 expression is restricted to a subset of type 2 fibers (2). Recommended Applications WB, IHC, IP Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 IHC: 1:100 - 250 IP: 1:40 Species Reactivity * Human, Mouse, Rat * *Cross reactivity determined by western blot only. Products Data A. Western blot analysis on human skeletal muscle lysate using anti-Alpha-Actinin 2 RabMAb (cat. # 2340-1), dilution 1:50,000 B. Immunohistochemical analysis of paraffin-embedded human muscles using anti-Actinin 2 RabMAb (cat. #2340-1). Specificity A synthetic peptide corresponding to residues near the C-terminus of human Alpha-Actinin 2 was used as an immunogen. |
| 性狀 | 【產(chǎn)品類型】Rabbit Monoclonal IgG
【反應特異性】Human , Mouse , Rat 【克隆 ID】EP2530Y 【用途】WB , IHC , IP 【產(chǎn)品性狀】 【陽性對照】 【產(chǎn)品濃度】 【細胞定位】 【抗原分子量】100 kDa |
| 貯存 | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
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