小程序掃碼下單
本網(wǎng)站銷售的所有產(chǎn)品僅用于工業(yè)應(yīng)用或者科學(xué)研究等非醫(yī)療目的，不可用于人類或動(dòng)物的臨床診斷或者治療，非藥用，非食用。
EGFR (C-term)
英文名：Rabbit Monoclonal IgG
Cas號(hào)：
Cas號(hào)：
檢測(cè)信息查詢
| 貨號(hào) | 規(guī)格 | 貨期 | 庫(kù)存 | 價(jià)格 | 促銷價(jià) | 訂購(gòu) |
| 1308113539-100ul | 現(xiàn)貨 | 0 | ￥0 |
| 別 名 | Recept o r tyrosine-protein kinase ErbB-1 |
| Cas號(hào) | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 產(chǎn)品參數(shù) | 【產(chǎn)品介紹】Epidermal growth fact o r recept o r (EGFR) is
a 170 kDa transmembrane glycoprotein recept o r tyrosine kinase that, activated by epidermal growth fact o r (EGF), affects cell growth a n d differentiation (1). Binding of EGF o r TGF alpha to EGFR activates tyrosine kinase activity of the recept o r (2). The carboxy terminal tyrosine residues on EGFR, Tyr 1068, Tyr 1148, a n d Tyr 1173, are the maj o r sites of autophosph o r ylation, which occurs as a result of EGF binding (3). Once activated, EGFR phosphotyrosines Y-1068 a n d Y-1173 mediate the binding of Grb2 to the EGFR. Another autophosph o r ylation site, Tyr 1086, is situated within the cytoplasmic domain, a n d is phosph o r ylated to a higher extent by c-Src than by EGFR (4). WB: 1:10,000 ICC: 1:50 Flow Cytometry: 1:10 IP: 1:30 A. Western blot analysis on A431 cell lysate using anti-EGFR (C-term) RabMAb (cat. #2235-1); dilution 1:10,000. B. Immunoflu o r escent staining of A431 cells using anti-EGFR (C-term) RabMAb (cat. #2235-1). |
| 性狀 | 【反應(yīng)特異性】Human
【克隆 ID】E235 【用途】WB , ICC , FC , IP 【抗原分子量】170 kDa |
| 貯存 |
滬公網(wǎng)安備 31012002003054號(hào)