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Recombinant Human Angiopoietin-Related Protein 4, His (HEK293-expressed)
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| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308133027-10 μg | 0 | ¥1500 | ||||
| 1308133027-50 μg | 0 | ¥4200 |
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| 性狀 | Recombinant Human Angiopoietin-Related Protein 4, His (HEK293-expressed) 通過抑制脂蛋白脂肪酶 (LPL) 調節循環甘油三酯 (TG) 的分布。Angiopoietin-Related Protein 4是一種傳統的,非競爭性的LPL 抑制劑。
Synonyms rHuAngiopoietin-Related Protein 4, His; ANGPTL4; Angiopoietin-Related Protein 4 ; 重組人血管生成素樣蛋白4 Species Human Source HEK 293 Accession Q9BY76 Gene ID 51129 Molecular Weight 32-38 kDa AA Sequence HHHHHHPEMA QPVDPAHNVS RLHRLPRDCQ ELFQVGERQS GLFEIQPQGS PPFLVNCKMT SDGGWTVIQR RHDGSVDFNR PWEAYKAGFG DPHGEFWLGL EKVHSITGDR NSRLAVQLRD WDGNAELLQF SVHLGGEDTA YSLQLTAPVA GQLGATTVPP SGLSVPFSTW DQDHDLRRDK NCAKSLSGGW WFGTCSHSNL NGQYFRSIPQ QRQKLKKGIF WKTWRGRYYP LQATTMLIQP MAAEAAS Biological Activity Data is not available. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS, pH 7.4. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human Angiopoietin-Related Protein 4, His (HEK293-expressed) (rHuAngiopoietin-Related Protein 4, His) to 100 μg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Human Angiopoietin-Related Protein 4, His (HEK293-expressed) (rHuAngiopoietin-Related Protein 4, His) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Angiopoietin-like proteins (ANGPTLs) represent a family of eight secreted glycoproteins that show structural homology to angiopoietins and carry distinct physiological functions, including putative roles in lipid metabolism, expansion of stem cells, inflammation, tissue remodeling and angiogenesis. In recent years, three ANGPTLs, ANGPTL3, ANGPTL4 and ANGP-TL8, have been shown to play a role in lipid metabolism and in the regulation of plasma lipid levels. ANGPTL4 and ANGPTL8 form a complex when refolded together and that ANGPTL4 in that complex loses its ability to inactivate LPL. Angiopoietin-like protein 4 (ANGPTL4) is a secreted 50 kD protein that modulates the disposition of circulating triglycerides (TG) by inhibiting lipoprotein lipase (LPL). ANGPTL4 is a positive acute phase protein and its increase could contribute to the hypertriglyce-ridemia that characteristically occurs during the acute phase response by inhibiting LPL activity. |
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