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Recombinant Human AG-3, His (HEK293-expressed)
英文名:
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| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308132987-10 μg | 0 | ¥3200 | ||||
| 1308132987-50 μg | 0 | ¥9800 |
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| 性狀 | Recombinant Human AG-3, His (HEK293-expressed) 是帶有 N 末端 His 標簽的人重組 AG-3,在 HEK293 細胞中表達。
Synonyms rHuAG-3, His; HAG-3; AGR3; AG3 ; 重組人 AG-3,His (HEK293 細胞表達) Species Human Source HEK 293 Accession Q8TD06 Gene ID 155465 Molecular Weight Approximately 16.0 kDa AA Sequence IAIKKEKRPP QTLSRGWGDD ITWVQTYEEG LFYAQKSKKP LMVIHHLEDC QYSQALKKVF AQNEEIQEMA QNKFIMLNLM HETTDKNLSP DGQYVPRIMF VDPSLTVRAD IAGRYSNRLY TYEPRDLPLL IENMKKALRL IQSELHHHHH H Biological Activity Data is not available. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against 20 mM Tris-HCl, 150 mM NaCl, 2 mM EDTA, pH 8.5. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human AG-3, His (HEK293-expressed) (rHuAG-3, His) to 100 μg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Human AG-3, His (HEK293-expressed) (rHuAG-3, His) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background AG-3 (Anterior gradient 3; AGR3), a member of the protein disulfide isomerase (PDI) family, shares high sequence homology with AG-2. AG-3 is overexpressed in breast, prostate and ovarian cancer. Combined AG-3 and acid mucopolysaccharides could serve as a diagnostic marker for well-differentiated intrahepatic cholangiocarcinoma. AG-3 expression was correlated with the level of differentiation in the serous type of ovarian cancer. AGR3 activates Wnt/β-catenin signalling and promotes the nuclear translocation of β-catenin to upregulate stemness related genes[1]. |
| 貯存 |
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