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Recombinant Mouse Stromal-Cell Derived Factor-1 beta/CXCL12 (CHO-expressed)
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| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308132920-10 μg | 0 | ￥3800 | ||||
| 1308132920-10 μg | 0 | ￥3800 |
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| 性狀 | Recombinant Mouse Stromal-Cell Derived Factor-1 beta/CXCL12 (CHO-expressed) 是 CXC 趨化因子家族成員，能夠結合 CXCR4、CXCR7，與腫瘤的增殖、存活、血管生成、轉移及免疫抑制有關。
Synonyms rMuSDF-1β/CXCL12; SDF-1; PBSF; C-X-C motif chemokine 12; TLSF ; 重組小鼠基質細胞衍生因子-1β/CXCL12 (CHO-expressed) Species Mouse Source CHO Accession P40224 Gene ID 20315 Molecular Weight Approximately 8.5 kDa AA Sequence KPVSLSYRCP CRFFESHIAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRL KM Biological Activity The EC50 is <2.5 μg/mL as measured on Ca2+ mobilization assay in CHO-K1/Gα15/mCXCR4 cells (human Gα15 and mCXCR4 stably expressed in CHO-K1 cells). Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Mouse Stromal-Cell Derived Factor-1 beta/CXCL12 (CHO-expressed) (rMuSDF-1β/CXCL12) to 100 μg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Mouse Stromal-Cell Derived Factor-1 beta/CXCL12 (CHO-expressed) (rMuSDF-1β/CXCL12) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background CXCL12 belongs to the CXC chemokine family, and is expressed in two isoforms, SDF-1α and SDF-1β, binds to CXCR4 and CXCR7. CXCL12/CXCR4 signal is implicated in tumor proliferation, survival, vascularization, metastasis, and immunosuppression[1]. |
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