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度伐單抗
英文名:Durvalumab
Cas號(hào):1428935-60-7
Cas號(hào):1428935-60-7
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| 貨號(hào) | 規(guī)格 | 貨期 | 庫(kù)存 | 價(jià)格 | 促銷價(jià) | 訂購(gòu) |
| 13081324891-1mg | 99.50% | 0 | ¥5400 | |||
| 13081324891-5mg | 99.50% | 0 | ¥11400 |
| 別 名 | |
| Cas號(hào) | 1428935-60-7 |
| M D L | |
| 分子式 | |
| 分子量 | |
| 產(chǎn)品參數(shù) | Description
Durvalumab (MEDI 4736) is an humanized anti-PD-L1 monoclonal antibody[1]. Durvalumab (MEDI4736) completely blocks the binding of PD-L1 to both PD-1 and CD80, with IC50s of 0.1 and 0.04 nM, respectively[2]. IC50 & Target IC50: 0.1 nM (PD-L1/PD-1), 0.04 nM (PD-L1/CD80)[2] |
| 性狀 | Durvalumab (MEDI 4736) 是一種人源化的抗 PD-L1 蛋白單克隆抗體。Durvalumab (MEDI 4736) 完全阻斷 PD-L1 與 PD-1 和 CD80 結(jié)合, IC50 分別為 0.1 和 0.04 nM。 |
| 貯存 | Storage Please store the product under the recommended conditions in the Certificate of Analysis. References [1]. Faiena I, et al. Durvalumab: an investigational anti-PD-L1 monoclonal antibody for the treatment of urothelial carcinoma. Drug Des Devel Ther. 2018 Jan 23;12:209-215. [2]. Stewart R, et al. Identification and Characterization of MEDI4736, an Antagonistic Anti-PD-L1 Monoclonal Antibody. Cancer Immunol Res. 2015 Sep;3(9):1052-62. |
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