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Cytokeratin 4 (KRT4)
英文名：Rabbit Monoclonal Antibody
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檢測信息查詢
| 貨號 | 規(guī)格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308113487-100ul | 現(xiàn)貨 | 0 | ￥0 |
| 別 名 | KRT4 antibody, CK4 antibody, CYK4 antibody, FLJ31692 antibody, K4 antibody, Keratin, type II cytoskeletal 4 antibody, Type-II keratin Kb4 antibody |
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| 產(chǎn)品參數(shù) | 【產(chǎn)品介紹】Keratins are a family of structurally
related proteins that form the intermediate filament cytoskeleton in epithelial cells. White sponge nevus (WSN) is a benign autosomal dominant disorder which affects non-cornifying stratified squamous epithelial. Keratins are expressed in pairs by epithelial cells in a tissue and cell specific manner. The major differentiation specific keratins of the buccal mucosa, nasal, esophageal and anogenital epithelia are CK-4 and CK-13. The tissue distribution and nature of the lesions in patients affected by WSN suggested that mutations in CK-4 and/or CK-13 might be responsible for this disorder (1). K4 and K13 form heterodimers in normal epithelial cells. In humans, K4 is present in all layers of the epidermis at 10 weeks and gradually disappears, starting from the basal layers at 15 weeks and becoming totally absent at around 20 weeks. This period corresponds to the early fetal period when melanoblasts derived from the neural crest migrate through the dermis into the basal layer of the epidermis (2). Recommended Applications WB, IHC, ICC, IP, FC Applications and Recommended Dilution Factors WB: 1:500 - 1000 IHC: 1:100 - 250 ICC: 1:50 - 100 IP: 1:10 - 100 FC: 1:100 - 500 Species Reactivity * Human *Cross reactivity determined by western blot only. Products Data A. Western blot analysis on A431 cell lysate using anti-Cytokeratin 4 RabMAb (cat. # 1994-1). B. Immunohistochemical staining of paraffin-embedded cervical carcinoma using anti-Cytokeratin 4 RabMAb (cat. #1994-1). Specificity A synthetic peptide corresponding to residues on the C-terminus of human Cytokeratin 4 was used as an immunogen. |
| 性狀 | 【反應(yīng)特異性】Human
【克隆 ID】EP1599Y 【用途】WB , IHC , ICC , FC , IP 【抗原分子量】59kDa |
| 貯存 | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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