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CD205 (LY75)
英文名：Rabbit Monoclonal Antibody
Cas號：
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| 貨號 | 規(guī)格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308113415-100ul | 現(xiàn)貨 | 0 | ￥0 |
| 別 名 | LY75 antibody, CD205 antibody, CLEC13B antibody, DEC-205 antibody, GP200-MR6 antibody, LY-75 antibody, Lymphocyte antigen 75 antibody, C-type lectin domain family 13 member B antibody, DEC-205 antibody, gp200-MR6 antibody |
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| 產品參數(shù) | 【產品介紹】CD205 is a type I C-type lectin-like
molecule that acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (1, 2). It functions to deliver antigen to dendritic cells for presentation on MHC class II and cross-presentation on MHC class I. Thus, CD205 plays an important role in CD4 and CD8 T cell tolerance induction to self-antigen both in the periphery and in the thymus. It is expressed at high levels on cortical thymic epithelium, thymic medullary DCs (CD11c+ CD8+), and subsets of peripheral DCs (CD11c+ CD8+ splenic/lymph node DCs, dermal/interstitial DCs, and Langerhans cells) (2). In addition, CD205 causes reduced proliferation of B-lymphocytes (1). Recommended Applications WB, IHC, ICC, IP Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 IHC: 1:250 - 500 ICC: 1:100 - 250 IP: 1:10 - 100 Species Reactivity * Human, Mouse *Species cross-reactivity is based on WB analysis Products Data Western blot analysis on (A) human thymus, (B) human lymph node, (C) human tonsil, and (D) mouse thymus lysates using anti-CD205 RabMAb (cat. #3912-1). Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD205 RabMAb (cat. #3912-1). Specificity A synthetic peptide corresponding to residues in the intracellular domain of human CD205 was used as an immunogen. |
| 性狀 | 【反應特異性】Human , Mouse
【克隆 ID】EPR5233 【用途】WB , IHC , ICC , IP 【抗原分子量】205kDa |
| 貯存 | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |
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