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ADAM15
英文名：Rabbit Monoclonal Antibody
Cas號(hào)：
Cas號(hào)：
檢測(cè)信息查詢
| 貨號(hào) | 規(guī)格 | 貨期 | 庫(kù)存 | 價(jià)格 | 促銷價(jià) | 訂購(gòu) |
| 1308113308-100ul | 現(xiàn)貨 | 0 | ￥0 |
| 別 名 | ADAM15 antibody, MDC15 antibody, Disintegrin and metalloproteinase domain-containing protein 15 antibody, Metargidin antibody |
| Cas號(hào) | |
| M D L | |
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| 分子量 | |
| 產(chǎn)品參數(shù) | 【產(chǎn)品介紹】ADAM15 is a member of the ADAM (a
disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. ADAM15 contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, it specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that ADAM15 may function in cell-cell adhesion as well as in cellular signaling (1). Recommended Applications WB, IHC, IP Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 IHC: 1:250 - 500 IP: 1:10 - 100 Species Reactivity * Human *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on SW480 cell lysate using anti-ADAM15 RabMAb (cat. #5135-1). Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-ADAM15 RabMAb (cat.# 5135-1). Specificity A synthetic peptide corresponding to residues in the extracellular domain in human ADAM15 was used as an immunogen. |
| 性狀 | 【反應(yīng)特異性】Human
【用途】WB , IHC , IP 【抗原分子量】110 (pro-ADAM15) / 90 kDa (mature) |
| 貯存 | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |
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