小程序掃碼下單
本網站銷售的所有產品僅用于工業應用或者科學研究等非醫療目的，不可用于人類或動物的臨床診斷或者治療，非藥用，非食用。
4E-BP1 (EIF4EBP1)
英文名：Rabbit Monoclonal Antibody
Cas號：
Cas號：
檢測信息查詢
| 貨號 | 規格 | 貨期 | 庫存 | 價格 | 促銷價 | 訂購 |
| 1308113293-100ul | 現貨 | 0 | ￥0 |
| 別 名 | EIF4EBP1 antibody, 4E-BP1 antibody, 4EBP1 antibody, BP-1 antibody, MGC4316 antibody, PHAS-I antibody, Eukaryotic translation initiation factor 4E-binding protein 1 antibody, Phosphorylated heat- and acid-stable protein regulated by insulin 1 antibody |
| Cas號 | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 產品參數 | 【產品介紹】4E-BP1 (eIF4E-binding protein) also known
as PHAS, is a 10-12 kDa acidic protein that compete with eIF4G for binding of eIF4E to the mRNA 5' cap structure (1). Binding of the 4E-BPs to eIF4E is reversible and is dependent on the phosphorylation status of 4E-BP. Non-phosphorylated 4E-BP1 will bind strongly to eIF4E, while the phosphorylated form will not (2). Akt, TOR, MAP kinase, S6 kinase, and Cdc2 are known kinases capable of inactivating 4E-BP1 binding to eIF4E by phosphorylating either threonines 35, 45, 69 or serine 64. However, not all phosphorylation events equally block the 4EBP1-eIF4E interaction (3-4) Recommended Applications WB, IHC, ICC, IP, FC Applications and Recommended Dilution Factors WB: 1:500 -1000 IHC: 1:100-250 ICC: 1:100-250 IP: 1:50 FC: 1:20 Species Reactivity * Human, Mouse, Rat *Cross reactivity determined by western blot only. Specificity A synthetic peptide corresponding to residues near the N-term of human4E-BP1 was used as immunogen. |
| 性狀 | 【反應特異性】Human , Mouse , Rat
【克隆 ID】Y329 【用途】WB , IHC , ICC , FC , IP 【抗原分子量】15-20kDa |
| 貯存 | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
滬公網安備 31012002003054號