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Fumitremorgin C
英文名:Fumitremorgin C
Cas號(hào):118974-02-0
Cas號(hào):118974-02-0
檢測(cè)信息查詢
| 貨號(hào) | 規(guī)格 | 貨期 | 庫(kù)存 | 價(jià)格 | 促銷價(jià) | 訂購(gòu) |
| 13081129741-0.25mg | 98% | 0 | ¥2160.4 |
| 別 名 | Tryptoquivaline FTC |
| Cas號(hào) | 118974-02-0 |
| M D L | MFCD08702652 |
| 分子式 | C22H25N3O3 |
| 分子量 | 379.45 |
| 產(chǎn)品參數(shù) | |
| 性狀 | Fumitremorgin C is a specific inhibitor of breast cancer resistance protein (BCRP/ABCG2) multidrug efflux transporter. At 5 μM, it significantly potentiates the toxicity of the chemotherapeutic drugs mitoxantrone, doxorubicin, and topotecan in S1-M1-3.2 colon carcinoma cells. Fumitremorgin C reverses multidrug resistance in cells overexpressing BCRP but not P-glycoprotein (ABCB1) or MRP1 (ABCC1).
Fumitremorgin C is a specific inhibitor of breast cancer resistance protein (BCRP/ABCG2) multidrug efflux transporter. At 5 μM, it significantly potentiates the toxicity of the chemotherapeutic drugs mitoxantrone, doxorubicin, and topotecan in S1-M1-3.2 colon carcinoma cells. Fumitremorgin C reverses multidrug resistance in cells overexpressing BCRP but not P-glycoprotein (ABCB1) or MRP1 (ABCC1). |
| 貯存 | 儲(chǔ)存溫度:?20°C |
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